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Radicals are a major component of ROS that can attack lipids, especially polyunsaturated fatty acids (PUFAs), in a process called lipid peroxidation (Box 1)

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demonstrated the use of transdermal delivery of glutathione by loading it into the hyaluronic acid microneedles.[] GLUTATHIONE POLYMER FILMS Recent research focuses on the use of GSH responsive linkers to prepare polymers which degrade upon the exposure to millimolar concentrations of GSH, and the use of these polymers to prepare particles that disassemble at these concentrations