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Upstream regulation of mTORC2 mTORC2 is mainly controlled by insulin and growth factors (Fig

This work was supported by Department of Health and Human Services/NIH/National Cancer Institute grants to RKA (P30 CA016520-45

As this method uses formaldehyde fixation to stabilize proteins complexes, it is particularly suited to study chromatin and transcription factor complexes (Mohammed et al., 2016)

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This is one of the most efficient energy-producing pathways in cells, therefore, high energy demanding tissues, such as heart and kidney, mainly rely on fatty acids utilization (Console et al., 2020)