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This field integrates principles from biology, genetics, nutrition, exercise physiology, and medical science to address the intricate and multifaceted aspects of aging, aiming to enable individuals to live longer and healthier lives

Then we ask, given the inevitable decline of all those features, if you want to have those parameters at 90, what do they need to look like at age 50

This suggests that GM changes in OP are not merely compositional but functional, influencing the host metabolome in ways that may directly affect bone remodeling

Trends Mol Med 11 , 3742 (2005)

Zhao, L., Li, Z., Vong, J.S.L., Chen, X., Lai, H.-M., Yan, L.Y.C., Huang, J., Sy, S.K.H., Tian, X., Huang, Y., Chan, H.Y.E., So, H.-C., Ng, W.-L., Tang, Y., Lin, W.-J., Mok, V.C.T., Ko, H., 2020