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In CF animal models, increased TBARS have been demonstrated in the lung tissue of Cftr -KO mice, reflecting localized oxidative damage within affected organs (Velsor et al., 2001), although TBARS in BAL fluid (BALF) were below detection limits in both Cftr -KO and WT mice

Reproductive system diseases Long regarded as a general redox maintenance enzyme, SQOR has recently been identified as a key factor in male reproductive health

TAK1 was originally identified as a potential mediator of TGF- signal transduction and has been reported to be an upstream kinase of NF-B 46,47

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