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Brain Summary Keywords Parkinsons disease, mitochondrial dysfunction, bioenergetics, mitochondrial quality control, therapy Citation Gao X-Y, Yang T, Gu Y and Sun X-H (2022) Mitochondrial Dysfunction in Parkinsons Disease: From Mechanistic Insights to Therapy

FIGURE 1 Inflammation Neuroinflammation is a key pathophysiological mechanism of secondary injury, as it can produce neurotoxic effects on neurons through oxidative stress, apoptosis, and excitotoxicity (Faden et al., 2016)