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Jiang D et al

Elevated beta-glucuronidase levels often result in higher levels of proliferative estrogen metabolites such as 4-OH Estrone and 16A-OH Estrone and negatively skew important ratios such as 2-OH (E1 + E2)/16a-OH E1, which is believed to be an independent risk factor for breast cancer

And if it happens to you for any reason- car accident, sports-related, sexual activity- it can cause damage to the soft tissue, nerve and blood supply of the penis and needs to be evaluated immediately

McElwee KJ, Freyschmidt-Paul P, Hoffmann R, Kissling S, Hummel S, Vitacolonna M, et al

Whole-cell current clamp recordings were made with a headstage (CV-7B) connected to a computer-controlled amplifier (MultiClamp 700B, Axon Instruments), digitized through a Digidata 1440A Analog/digital converter and acquired at a sampling rate of 10 kHz