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We hypothesize that the brain energy gap, first described by Cunnane et al., [39] explains the increased susceptibility to developing delirium in the elderly critically ill patient population with preexisting cognitive impairment, and that exacerbation of this brain energy gap as a result of delirium contributes to the progression of preexisting cognitive impairment that is often apparent once delirium resolves (Fig

Abstract Tripeptide GSH is associated not only with the control and maintenance of redox cell homeostasis, but also with the processes of detoxification, proliferation, cell differentiation, and regulation of cell death

For people with chronic conditions such as diabetes, inflammatory disorders, or autoimmune issues, glutathione offers additional antioxidant and anti-inflammatory support

STAT3 is most closely associated with immunosuppressive effects and is the only family member whose genetic defect leads to embryonic necrosis (OShea et al., 2013)

*Correspondence: Melina A