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Belujon and Grace (2017) systematically elaborated in their review on the central role of dopamine system dysregulation in MDD, noting that anhedonia, a core symptom of depression, is closely related to mesolimbic dopamine pathway dysfunction

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It is important to distinguish between a negative side effect and your body simply recalibrating its internal processes

76 For example, researchers can influence tumor cell growth and survival by modulating energy metabolism pathways, and clinical studies integrating metabolic inhibitors into cancer treatment protocols are transforming metabolic insights into therapeutic strategies