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As a result, early diagnosis and intervention are crucial for achieving full recovery [30]

V., Verhoeven, G

"Glutathione as a skin whitening agent: Facts, myths, evidence and controversies." Indian J Dermatol Venereol Leprol

In cells from articular cartilage, synovial tissue and fluid from patients with OA, elevated levels of the transcription factor hypoxia inducible factor (HIF)-1 were found, indicating hypoxic conditions, that are associated with progressive joint damage (114, 115)

A particularly promising approach involves the rational design of combination therapies that synergistically integrate ferroptosis inducers with emerging immunotherapeutic modalities, such as immune checkpoint inhibitors, chimeric antigen receptor T-cell therapies, or cancer vaccines