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Yamashita S-i, Sugiura Y, Matsuoka Y, Maeda R, Inoue K, Furukawa K, et al

Archived from the original on August 19, 2014

Mittendorfer B

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By analyzing tumor-specific receptor expression patterns through multi-omics approaches (e.g., transcriptomics, proteomics), clinicians can identify optimal targeting ligandssuch as folate for FR-overexpressing tumors or transferrin for TfR-dominant malignanciesthereby maximizing tumor-specific uptake while minimizing off-target effects [312]