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Description

This cellular demise can subsequently diminish ECM synthesis, which in turn, exacerbates the degradative changes within the IVD microenvironment, perpetuating a cycle that further compromises the viability of NPCs

Cytoskeleton 64 , 794807 (2007)

Questa soppressione di vitale importanza nelle ferite croniche e nell' invecchiamento cutaneo (inflammaging) , dove l'infiammazione persistente degrada la matrice extracellulare e impedisce la corretta riepitelizzazione