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coli express a type III RNR that can use either reducing power supplied by Trx or Grx, or can directly use the oxidation of formate, to generate a thiyl radical in the RNR active site and thereby drive the reduction of ribonucleotides [87, 88]

Glutathione S-transferases are a family of enzymes involved in the detoxification of endogenous and xenobiotic compounds 33

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Wang Y, Wei Z, Pan K, Li J, Chen Q

An example of this is the situation that occurs in HIV/AIDS patients who experience a persistent drop in tissue glutathione levels

Results: Comparative analysis of weight kinetics revealed an increase of a median weight from 32.8 kg on day 0 to 34.2 kg on day +100 (p = 0.01) in PEG group whereas in the non-PEG group median weight on the respective time-points declined from 41.5 kg to 37.3 kg (p = 0.006)