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Development of novel biosensors to study receptor-mediated activation of the G-protein alpha subunits G(s) and G(olf)

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Additionally, preclinical and clinical search terms were combined with the type of animal model (self-administrationconditioned place preference) or disorders (substance use disordersaddictionsubstance abusedependence)

In addition to genetic approaches, a pharmacological tool that has frequently been used to deplete glutathione is buthion- ine sulphoximine (BSO), a specic inhibitor of g-ECS (Grif- th & Meister 1979)