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And a common mistake made by doctors is to assess serum B12 only

ClinicalTrials.gov identifier: NCT05730036

B vitamins are necessary for the proper functioning of the methylation cycle, DNA synthesis, repair and maintenance of phospholipids and generally essential for healthy skin, muscles, brain, and nerve functionality

Treatment of vitamin b(12)-deficiency anemia: oral versus parenteral therapy

This metabolic shift is characterized by upregulation of rate-limiting glycolytic enzymes such as pyruvate kinase M2 isoform (PKM2) and hexokinase (HK), leading to elevated production of glycolytic end-products, including pyruvate and lactate ( ex vivo , and increased activities of HK, PKM2, and lactate dehydrogenase (LDH) have been reported in mouse models of AKI ( Collectively, these findings indicate a metabolic shift from FAO to glycolysis in TECs during AKI