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Increased frataxin expression in patient derived lymphoblast was observed after excising the GAA expansion repeat in one allele using zinc finger nuclease [29]

1d, but showing the proportion of molecules generated by DeepMet that are also BioTransformer products, as a function of the number of rule-based transformations applied sequentially to the original metabolite and with or without the removal of structures also present in ChEMBL

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Peptides can induce hormonal imbalances, potentially causing side effects such as mood fluctuations and decreased sexual performance

Thus, with disruption of lipolysis by removal of HSL, there is a drastic reduction in lipogenesis, which could allow a more efficient export of fatty acids released by lipolysis out of the cell