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Studies found that fat mass reduction occurred without corresponding losses in lean tissue, indicating a muscle-sparing effect

Vigilanza, P., Aquilano, K., Baldelli, S., Rotilio, G

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The efficacy of pemetrexed was evaluated in Study JMCH (NCT00005636), a multicenter, randomized (1:1), single-blind study conducted in patients with MPM who had received no prior chemotherapy