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Elevated plasma iron levels, in turn, lead to an increase in iron transport into parenchymal cells, particularly hepatocytes, pancreatic cells, and cardiomyocytes, leading to organ iron overload

Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-sma

Free Radic Biol Med 14:8590 Winterbourn CC (2003) Radical scavenging by thiols: biological significance and implications for redox signaling and antioxidant defense

Elevated IgE levels can indicate the presence of allergies, which may be associated with increased histamine release

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