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Gumbel, who previously worked for NBC Sports and was the older brother of former TODAY co-host Bryant Gumbel, passed away peacefully surrounded by much love after a courageous battle with cancer," his wife, Marcy, and daughter, Michelle, said in a statement

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Acetylcholine from brainstem nuclei might exert a profound modulatory effect on both populations of VTA neurons through the activation of nAChRs