glucuronidation glutathione General Principles of Pharmacology: Drug Metabolism Phase II consists of covalent

Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial glucorindation vs glutathione Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron Drug Conjugate Analysis using Glucuronidases Glucuronidation Part 1 YouTube Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron activated dissociation (EAD)

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