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In obesity, abnormal adipose metabolism transports large amounts of free fatty acids to the liver, increasing hepatic fat synthesis, decreasing fat breakdown, and ultimately causing hepatic steatosis

305,306 In a study involving 37 participants with fibromyalgia and IBS, 31 reported a reduction in fibromyalgia symptoms after four weeks on an MSG- and aspartame-free diet

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While available studies suggest a favorable tolerability profile, long-term safety beyond 12 weeks still requires additional research