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All animal handling procedures are in agreement with the ARRIVE guidelines from the National Center for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) 19 throughout the experimental period (eight weeks)

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Critically, we demonstrated that suppression of SLC7A11 transcription results from mut-p53 binding and interfering with the activity of the master antioxidant transcription factor NRF2, a mechanism which is separate from the transcriptional regulation of SLC7A11 by wt-p53 described by Jiang et al

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Cysteine adalah sulfur sulfhidril, mendapatkannya sangat penting pada unsur ini