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Furthermore, while in 2D/unconfined environments breast cancer cells maintain a mesenchymal migration phenotype characterized by actin-rich protrusions and adhesion to the substrate [7], in confinement, cells switch to an amoeboid/bleb-based migration mode [152, 164, 165]

The answer to can you bill cpt code 20610 twice in a single encounter depends on whether the two procedures were performed on different joints: two different joints mean two separately reportable units of CPT 20610 with appropriate modifiers, while the same joint treated twice means one unit regardless of how many times the needle was inserted

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