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Mammalian target of rapamycin (mTOR) pathways in neurological diseases

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Initially ACE2 plays a protective role against the harmful effects of angiotensin II (Ang II) (inflammation, fibrosis, oxidative stress, vasoconstriction, cancer) by transforming Ang II into Ang 1-7, which, acting on its receptor Mas, counteracts the effects of Ang II [18]