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Description

& de S Vieira, R

[9,18] Although pharmacologic approaches are the most important treatment strategies for MDD, response rates to the first-line antidepressants are moderate and remission is observed in about 3045% of patients

This effect occurs through a direct and IGF-I-mediated mechanism

Lwenberg M, de Boer NKH, Hoentjen F

GSH reaches millimolar levels (110 mM) within cells, micromolar levels (1030 M) in plasma, and its low redox potential (E 0 = 240 mV) makes GSH an ideal cellular redox buffer 581,582