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FIGURE 3 On the other, hyperglycemia also induces metabolic alterations, resulting in the disturbance of protein, fat, and carbohydrate metabolism

For example, it has demonstrated pro-estrogenic effects on bone and anti-estrogenic effects on breast tissue, although its safety in women with breast cancer has not yet been confirmed

doi: 10.1074/jbc.275.3.1829 26 SkandalisSS

Double knockout of MLKL and caspase-8 nearly abolishes IL-1 release and delays cell death, highlighting a multi-layered inflammasomecell death axis that ensures sustained inflammatory signaling