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Selenium also reduces inflammatory cytokine production by preventing NF-B from binding to its gene promoter (103)

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Hypoxia-inducible factor-1 perpetuates synovial fibroblast interactions with T cells and b cells in rheumatoid arthritis

The activity of peroxidases (ascorbate peroxidase: APX, EC 1.11.1.11 and guaiacol peroxidase: GPOX, EC 1.11.1.7) was assessed using a procedure in which 2 g of samples were homogenized at 4 C in 10 mL of 50 mM potassium phosphate buffer (pH 7.0) containing 1 mM EDTA (ethylenediaminetetraacetic acid), 1% PVP (polyvinylpyrrolidone), and 1 mM PMSF (phenylmethylsulfonyl fluoride)