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The potential positive results from such a study are strongly suggested by our results

The recruitment of microglia in the vicinity injured neuronal cells and their subsequent activation soon after the neuronal injury occurs seems to be found long before the clinical onset of CNS injury and may contribute to both neuronal damage and pathogenesis [65,66]

One of the key mechanisms through which nicotinamide may exert these protective effects is by restoring the levels of nicotinamide adenine dinucleotide (NAD+), which is critical for mitochondrial metabolism and energy production