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10.1016/S0022-2836(02)00262-0 76 SamdaniA.VetrivelU

In metabolic disease contexts, studies have found that supraphysiological doses of coenzyme Q 10 (CoQ 10 ) can specifically upregulate SQOR expression and simultaneously inhibit key enzymes (CBS and CSE) in the transsulfuration pathway, thereby reshaping the serinefolate cycle and nucleotide metabolism (Gonzlez-Garca et al., 2020)

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Metabolomic disorders: Confirmed presence of potentially treatable abnormalities in patients with treatment refractory depression and suicidal behavior