mk571 glutathione mrp1

mk571 glutathione mrp1 inhibitor MK-571 shifts cellular thiol pools, further potentiating MRP1-Dependent Extracellular Release of Glutathione

Name: mk571 glutathione mrp1 inhibitor MK-571 shifts cellular thiol pools, further potentiating MRP1-Dependent Extracellular Release of Glutathione
Brand: hgidocs.co
SKU: 54647829727
Price: 21.43 USD
Availability: InStock
Rating: 4.2826 (11 reviews)

MRP1 Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia Reperfusion Circulation Research Nitrogen monoxide (NO) mediated iron release from cells is linked to NO induced glutathione efflux via multidrug resistance associated protein 1 PNAS MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1 expressing cancer cells ScienceDirect Transport of glutathione and glutathione conjugates by MRP1: Trends in Pharmacological Sciences Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease medRxiv

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Description

[2] The cationic (unbound) form is red and has an absorption spectrum maximum at 465 nm, whereas the anionic bound form has an absorption spectrum maximum at 595 nm