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BCAAs induce significant changes in genes and proteins associated with ferroptosis in neurons and increase lipid ROS levels, causing ferroptosis in primary cultured cortical neurons and ischemic tissue

have further revealed that allicin administration significantly reduces plasma homocysteine (Hcy) levels in patients with coronary heart disease ( DATS has emerged as a potential therapeutic agent through its ability to release hydrogen sulfide (H 2 S), a gaseous signaling molecule

In addition, the characteristics and interactions of human CNS diseases are too complex to construct complete mechanistic models in vitro, but only by constructing animal models of such diseases[194]