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Proton pump inhibitors, H2-receptor antagonists, metformin, and vitamin B-12 deficiency: clinical implications

Thus, adequate folate intake is essential for preventing depression, due to its role in the synthesis of dopamine and serotonin, as well as dementia, through the prevention of neuronal damage ( 7 Vitamin B12 Vitamin B12, also known as cobalamin, plays a crucial role in the biochemistry of the nervous system, contributing to essential processes such as the synthesis of DNA, S-adenosylmethionine (SAM), and succinyl-CoA, all of which support nerve cell function and overall neurological health (70, 71)

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Certain nutritional deficiencies are linked to dysfunction of the nervous system

Navab M, Berliner JA, Watson AD et al (1996) The Yin and Yang of oxidation in the development of the fatty streak