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E1 is a thiamin pyrophosphate (TPP)-dependent -ketoacid dehydrogenase, R -lipoic acid functions as a prosthetic group essential for E2 transacetylase activity, and E3 is a flavin adenine dinucleotide (FAD)-dependent dihydrolipoamide dehydrogenase ( Figure 4 )

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The German researchers named this new thiazolidine-containing cyclic peptide lugdunin, the name derived from the Latin name of their town

Recombinant proteins fused to the PA tag can be effectively purified using antibody-immobilized affinity columns

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