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Atopic dermatitis endotypes and implications for targeted therapeutics

Updated 11/8/2023

Most strikingly, lips-7 is induced in long-lived ctbp-1 mutants, and lips-7 depletion prevents this longevity, whereas another lipase is dispensable

Annals of the New York Academy of Sciences 854 (1998): 54-60

This demonstrates that AR activity in advanced CRPC is controlled by factors beyond protein abundance, which likely includes activating or inactivating gene mutations in AR and activity and abundance of AR cofactors and regulators (27, 28)