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Sivasamy V

Does 5-Amino-1MQ work the same way regardless of administration route

Patients with normal organ function were included, and those with unavailable busulfan PK data owning to difficulties in blood sampling were excluded

Although its efficacy is lower than methotrexate and cyclosporine, apremilasts favorable safety profile, particularly its low hepatotoxicity risk, makes it a valuable option for patients who require long-term systemic therapy and cannot tolerate immunosuppressants (Papp et al