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Over eight hundred epilepsy-related genes have been identified, with about 42% of them being metabolically related [3]

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Dysregulated glucose metabolism is well reported in humans and animal models of ALS 13,29 , with increased production of lactate, a hallmark of the Warburg effect 25 , emerging as an early disease event

In a clinical trial, TB4 at a dose of 0.03% applied topically to venous ulcers led to complete wound healing in 33.3% of patients, compared to 23.5% for placebo

These components are considered immunological distractors with pro-inflammatory activity, capable of causing dysbiosis and increased intestinal permeability (the so-called leaky gut syndrome), so favoring the development of autoimmune diseases [142]