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This is particularly crucial in highly secretory cells such as pancreatic -cells, where efficient insulin production depends on intact Golgi dynamics

*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, it is administered safely in wellness clinics under professional supervision

In addition, the enhanced expression and activity of HO-1 by glutathione was associated with an increase in the total protein expression of Nrf2 and its phosphorylation at serine 40 (p-Nrf2), whereas the expression of Keap1, a negative regulator of Nrf2, was reduced in a glutathione treatment concentration-dependent manner (Figure 3A)

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