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The 2018 paper in Biochemical Pharmacology gave obese mice a membrane-permeable NNMT inhibitor and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with the mice eating the same amount as before, and the authors noting the inhibitors did not impact total food intake nor produce any observable adverse effects [1]

AOD-9604 aids fat metabolism and healing

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[10] [12] These interactions are supported by pharmacokinetic studies, clinical observations, and drug interaction databases