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The observations concerning telomerase come from the cellular level and do not automatically translate to the organism

exons 6 and 7) suggesting that the position in the enzyme quaternary structure is the most important determinant for enzyme instability

Further, kinetic studies of seleno-GPxs have revealed that the rate constant for the reaction of hydroperoxides with the selenolate of Sec is twothree orders of magnitude higher than the combined rate constant of the successive reactions of selenenic acid with the two molecules of GSH [8,9,10,11,12,13,14,15,16,17,18]