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[Abstract] bioRxiv

doi: 10.3390/metabo12040352 99 MikiYTaketomiYKidoguchiYYamamotoKMuramatsuKNishitoYet al

e , Lysates from HEK293T cells transfected with TMEFF1-HA were subjected to immunoprecipitation with anti-HA and anti-IgG beads, and immunoblotted for NMHC-IIB, NMHC-IIA, Nectin-1, and TMEFF1

Intraperitoneal injection of UA (1 g/kg) to these rabbits increased blood glucose concentrations to hyperglycemic levels, and therefore, it has been suggested that UA exerts a diabetogenic action [33]

Nrf2 is the principal transcription factor in charge of protecting cells from oxidative stress through the regulation of cytoprotective genes, including the antioxidant GSH pathway, that controls GSH homeostasis by affecting de novo synthesis