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However, some have also attempted to generate NF1-pLGG patient-derived xenograft models (68, 83) and transgenic non-NF1-pLGG model (67)

12,14 This allows for a shift in macrophage activity from M1 (pro-inflammatory) to M2 (reparative)

Astragalus mongholicus Bunge extract improves ulcerative colitis by promoting PLCB2 to inhibit colonic epithelial cell pyroptosis

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Single-particle cryo-EM maps are available at the Electron Microscopy Data Bank (EMDB): EMD-65225 and EMD-65226