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Available studies have demonstrated that DIS has a protective effect against renal injury induced by diabetic and nephrotoxic drugs, mainly through the regulation of oxidative stress, inflammatory response, lipid metabolism and cellular autophagy (17,2932)

Lipid profiles (cholesterol and triglycerides) might improve more with dual agonists

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In each of these 3 studies, the treatment effect, as measured by differences between PROZAC 60 mg and placebo on median reduction from baseline in frequency of bulimic behaviors at endpoint, ranged from 1 to 2 episodes per week for binge-eating and 2 to 4 episodes per week for vomiting

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