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However, daily oral supplementation with GlyNAC, a combination of GSH precursor amino acids glycine and cysteine (provided as N-acetylcysteine, NAC), can correct glycine and cysteine deficiencies, restore impaired GSH synthesis, and increase intracellular GSH concentrations in older individuals [110,111,112]

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Because it is largely free of those binding proteins, the analog stays active far longer than native IGF-1 a substantially extended half-life and more sustained systemic exposure