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HSP27 This small heat shock protein plays a dual role in metabolic diseases

(Pharmaceutical Society of Great Britain) (March 2003)

There is still an ongoing debate on whether the three CTA models are interchangeable or whether there should be criteria guiding the choice of one over the other based on their peculiarities and the characteristics of the tested chemicals ( In the absence of approved test guidelines, the OECD issued two guidance documents endorsing the use of CTA based on SHE and Bhas 42 cells

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Results show that reduced GSH decreases cell adhesion resulting in an increased cell volume