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In contrast to the secretion and mRNA expression of t-PA, the secretion and gene expression of type 1 plasminogen activation inhibitor in human endothelial and smooth muscle cells is enhanced by homocysteine (Midorikawa et al, 2000)

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J., Seaman G

specific tendinopathy), validated biomarkers and functional outcomes, long term safety and immunogenicity surveillance, and pharmacovigilance for angiogenesis related adverse events