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NNMT is highly expressed in the white adipose tissue of individuals with obesity and diabetes, where it acts as a "metabolic brake," slowing down the rate at which cells burn energy

Eosinophilic meningitis and encephalitis are other disorders caused by this nematode

Science 310 (5749), 847850

Adjust dosages for patients weighing less than 50 kg (2, 3, 5)

In this paper, we present a new integrated model for hepatic glutathione metabolism including one-carbon metabolism and use it to investigate how the activation of certain enzymes by estradiol in one-carbon metabolism and glutathione metabolism leads to dramatic changes in reaction velocities and metabolite concentrations, including GSH and the GSH synthesis rate