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During the onset phase of acute inflammation, PUFAs are initially converted into pro-inflammatory bioactive lipids (e.g., prostaglandins, leukotrienes) during the first few hours or days post-injury (dpi) 11

20 shows Fer-1 analogs incorporating ester bioisosteres

Since other SCFAs, such as acetate, are implicated in cysteine production (69, 70), maybe butyrate can be an undisclosed cysteine source ( Figure 1 )

Montoya JG, Anderson JN, Adolphs DL, Bateman L, Klimas NG, Levine SM, et al