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doi: 10.1074/jbc.270.22.13138 92 PedruzziEHakimJGiroudJPPerianinA

Tight regulation ensures that carnitine levels are maintained within a range that supports metabolic demands without causing toxicity

According to the literature from the past 30 years, the main central nervous system manifestations of MMA are as follows: prominence of the ventricles 21 , myelination abnormalities 22 , cortical atrophy and sulcal widening 23,24 , periventricular white matter abnormalities 25 , internal capsule changes 26 , basal ganglia changes 27 , cerebellar atrophy, subcortical white matter changes, and thinning of the corpus callosum 28,29,30

(PubMed) Matalliotakis I, Koumantaki Y, Evageliou A, Matalliotakis G, Goumenou A, Koumantakis E

This process is crucial for fat metabolism, which helps promote weight loss in animals that are overweight or predisposed to gain weight easily