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Critical appraisal was conducted through detailed reading of the full text and focused on the following considerations: (1) possible violations of the correct temporal sequence, e.g., if respiratory symptoms or conditions could have been present from baseline and therefore co-occurred or preceded EC use

Cognitive behavioural healing cure mediation generated essential efficacies when varied results developed were merged on account of combined studies

Among those who switched to e-cigarettes, the risk of severe exacerbation was lower (aHR = 0.84

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