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Description

Type I IFNs enhance nearly all DCs functions, including promoting monocyte differentiation into DCs, facilitating DCs migration to secondary LNs, upregulating co-stimulatory activity of DCs, and augmenting their ability to cross-present antigens to T cells [96]

Additionally, we examine current clinical trials and discuss existing gaps and opportunities that warrant further consideration

Enrichment analysis GO enrichment, KEGG enrichment, Reactome enrichment, and Disease enrichment (human only) of cluster markers were conducted using KOBAS software, employing the Benjamini-Hochberg multiple testing adjustment