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This review summarizes recent advances in age-related metabolic reprogramming in ECs and its contribution to atherosclerosis, particularly focusing on the dysregulation of glycolysis, fatty acid metabolism, amino acid metabolism, and mitochondrial respiration induced by age and fluid shear stress

Long-term use of carbamazepine, phenytoin, and rifampin can significantly reduce the steady-state plasma concentrations of these drugs, leading to treatment failure

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doi: 10.1016/j.carbpol.2015.06.068 82 ZhangY.ChenC.CuiY.DuQ.TangW.YangW.et al

These cytokines activate inducible nitric oxide synthase (iNOS) enzymes, promoting the release of large volumes of NO